On 24 November 2006, Papaioannou premièred 2 in Athens, his first work following his creative direction of the Opening and Closing Ceremonies of the Athens 2004 Olympic Games. 2 was produced in collaboration with the e...展开lectronic music composer K.BHTA for the production company Elliniki Theamaton. A "dissection of the male psyche", the production commanded a large of amount of Greek press attention, not least for its open references to homosexuality. 2 proved a commercial success; its run was extended twice and over 100,000 tickets were sold in total.
The work seems to draw upon a range of influences, including the work of Jean Genet, René Magritte and Robert Wilson. Inspiration for the show also came partly from Papaioannou's experiences as a gay man in Greece. Contemporary magazine described 2 as an "inspiring" work that "captures the zeitgeist".
A DVD of 2, produced and directed for the screen by Athina Rachel Tsangari of HAOS FILM, was released on 11 December 2007 by Elliniki Theamaton and Modern Times.
(2002) His play, "2," was performed at the Eclipse Theatre Company in Chicago, Illinois with Steven Fedoruk in the cast. Nathaniel Swift was director.